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General medical words

What Does False Positive Mean on a Test Result?

False Positive · say it: fawls POZ-ih-tivAlso written: false-positive result, false alarm, false negative

Short answer

A false positive is a test result that says something is present when it is actually not; a false negative is the opposite.

What it means

No medical test is perfect. Sometimes a test signals that a condition or substance is present when it really is not. That is a false positive. When a test misses something that is really there, that is a false negative.

False positives are especially common with screening tests, which are designed to catch as many possible cases as they can. This is why a positive screening result is usually followed by a more specific confirmatory test.

False results can be caused by many things, including the test's limits, timing, cross-reaction with similar substances, medicines, or handling of the sample.

Where you may see it

  • Screening test results (cancer, pregnancy, drug and newborn screens)
  • Infection and antibody tests
  • Follow-up letters asking for repeat tests

📄 How it looks on a report

Screening result: Reactive. Confirmatory testing recommended.

🙅 What it does not mean

  • A positive screening test is not a diagnosis; it means more testing is needed.
  • Being asked for a repeat or confirmatory test does not mean the doctor expects bad news.
  • A false positive does not mean the lab made a mistake; it is a known limitation of tests.

🗒️ Questions to ask your doctor

🧾 Reports where you will see “False Positive”

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💊 Medicines whose labels mention “False Positive”

Plain-English explanations of each medicine, from its official FDA label.

  • Cephalexin

    a cephalosporin antibacterial medicine (an antibiotic that treats bacterial infections)

  • Gabapentin

    An antiepileptic (seizure) medicine. The label also describes it as a treatment for nerve pain after shingles.

🔗 Read more from trusted sources

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General information about a medical word, not advice about your own results. Ask the clinician who ordered the test what it means for you.